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Products PHYTOCHEMICALS FORSKOLIN
Products PHYTOCHEMICALS FORSKOLIN | FORSKOLIN |
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Forskolin extracted from Coleus has been well studied for its phytochemical properties. It shows Vasodilating, Cardiostimulatory, hypotensive activity, inhibits aggregation of human platelets, acts as brochodilator and decreases intraoccular pressure. It is indicated in conditions like hypertension, congestive heart failure and other cardiovascular diseases. Also in asthma, glaucoma, eczema, and psoriasis. Adenylate cyclase activating properties, used as leaning agent in obesity. Also in purification of Adenylate cyclase. Forskolin directly activates the enzyme Adenylate cyclase and raises cyclic AMP levels in a variety of tissues. Cyclic AMP is an important cell-regulating compound. Once formed it activates many other enzymes involved in diverse cellular functions. Under normal situations cAMP is formed when a stimulatory hormone (e.g., epinephrine) binds to a receptor site on the cell membrane and stimulates the activation of Adenylate cyclase. This enzyme is incorporated into all cellular membranes and only the specificity of the receptor determines which hormone will activate it in a particular cell. Forskolin appears to bypass this need for direct hormonal activation of Adenylate cyclase. As a result of this direct activation of Adenylate cyclase, intracellular cAMP levels rise. The physiological and biochemical effects of a raised intracellular cAMP level include: inhibition of platelet activation; inhibition of mast cell degranulation and histamine release; increased force of contraction of heart muscle; relaxation of the arteries and other smooth muscles; increased insulin secretion; and increased thyroid function.  Forskolin OR Coleonol, M.Wt. 410.50, Formula:C22H34O7 Description: Labdane diterpenes Color/Nature White to off-white crystalline powder, slightly bitter in taste. Synonyms: Coleonol, colforsin, boforsin Biomax Product Purity minimum 98%. |
